CW069|cas | DC Chem|Supplier|Price|Buy  

CW069|cas | DC Chem|Supplier|Price|Buy

DC Chemicals Supply: CW069, Cas:  ,Cat No. DC7392, Purity>98%, In stock.

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CW069|cas , Synonym name: CW069; CW 069, Chemical name:　(S)-2-(2-(benzylamino)-3-phenylpropanamido)-5-iodobenzoic acid, Molecule weight: 500.33, Molecule Formula: C23H21IN2O3

CW-069 is a novel and allosteric inhibitor of the microtubule motor protein HSET with IC50 value of 75 ± 20 μM; shows statistically significant selectivity over KSP.

CW069 increases multipolar spindles in N1E-115 cells with supernumerary centrosomes without altering bipolar spindle morphology in normal human dermal fibroblast cells. CW069 inhibits growth in cancer N1E-115 cells with IC50 of 10 μM, but not in NHDF or primary human bone marrow cells. [1]