WHI-P131(Janex 1)|DC Chemicasl

WHI-P131(Janex 1)|DC Chemicasl
Janex 1 selectively inhibits the tyrosine kinase activity of JAK3 with an IC50 value of 78 µM without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases (IC50 ≥350 µM).

Product name: WHI-P131(Janex 1) |Cat No. DC8077|Other names: WHI-P131，Janex 1|Cas: 202475-60-3|Molecule Weight: 297.31|Molecule Formular: C16H15N3O3| Purity: >98%

Janex 1 selectively inhibits the tyrosine kinase activity of JAK3 with an IC50 value of 78 µM without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases (IC50 ≥350 µM).Janex 1 induces apoptosis in JAK3-expressing human leukemia cell lines NALM-6 and LC1;19, but not in melanoma or squamous carcinoma cell lines.

For research and scientific purpose only, not for human use.