2015年6月22日星期一

PD 153035(AG-1517)|EGFR inhibitor|DC Chemicasl

PD 153035(AG-1517)|EGFR inhibitor|DC Chemicasl
PD 153035(AG-1517) is an ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM.

Product name: PD 153035(AG-1517) |Cat No. DC8078|Other names: PD 153035,AG-1517|Cas: 153436-54-5|Molecule Weight: 360.21|Molecule Formular: C16H14BrN3O2| Purity: >98%

An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation. Inhibits the growth of a number of cancer cell lines. An extremely useful tool for exploring EGF-mediated cellular signaling.

For research and scientific purpose only, not for human use.

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