AI-10-49 | CBFβ-SMMHC inhibitor|DC Chemicals

AI-10-49 | CBFβ-SMMHC inhibitor|DC Chemicals
AI-10-49 selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1.

Product name: AI-10-49 |Cat No. DC8064|Other names: AI-10-49|Cas: 1256094-72-0|Molecule Weight: 660.52|Molecule Formular: C30H22F6N6O5| Purity: >98%

AI-10-49 selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1. AI-10-49 restores RUNX1 transcriptional activity, displays favorable pharmacokinetics, and delays leukemia progression in mice. Treatment of primary inv(16) AML patient blasts with AI-10-49 triggers selective cell death.

For research and scientific purpose only, not for human use.