BI-78D3|cas 883065-90-5| DC Chem|Supplier|Price|Buy

BI-78D3|cas 883065-90-5| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: BI-78D3|cas 883065-90-5,Purity: >98% ,Cat No. DC7107, In stock.

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BI-78D3|cas 883065-90-5 ,Synonym:  ,Chemical name: 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1H-1,2,4-triazol-5-one ,Molecular Formula: C13H9N5O5S2 ,MW:379.37106

BI-78D3, cas 883065-90-5,Purity: >98%, Best Price and quality from DC Chemicals. Competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. Inhibits JNK interacting protein 1 (JIP1)-JNK binding (IC50 = 500 nM) and prevents JNK substrate phosphorylation. Blocks JNK-dependent Con A-induced liver damage and restores insulin sensitivity in a mouse model of type II diabetes.

Competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. Inhibits JNK interacting protein 1 (JIP1)-JNK binding (IC50 = 500 nM) and prevents JNK substrate phosphorylation. Blocks JNK-dependent Con A-induced liver damage and restores insulin sensitivity in a mouse model of type II diabetes.