AM580|cas 102121-60-8| DC Chem|Supplier|Price|Buy  

AM580|cas 102121-60-8| DC Chem|Supplier|Price|Buy

DC Chemicals Supply: AM580|cas 102121-60-8,Purity: >98% ,Cat No. DC7054, In stock.

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AM580|cas 102121-60-8 ,Synonym:  ,Chemical name: 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoicacid ,Molecular Formula: C22H25NO3 ,MW:351.44

AM580, cas 102121-60-8,Purity: >98%, Best Price and quality from DC Chemicals. A retinoic acid analog and selective RARα agonist

AM 580 is a selective retinoic acid analog, which is useful in vitro as a RARα agonist. Studies indicate that RARα increases the signaling of the RARα receptor to prevent intracellular and extracellular Amyloid β accumulation. In addition, this receptor increases the expression of disintegrin and metalloprotease. Since Amyloid β accumulation is a major finding in Alzheimer's disease (AD), AM 580 can be used to study this disease in vitro. AM 580 also induces the functions of IL-4, IL-5 and IL-13 and suppresses the production of IL-12 and IFNγ. Alternate studies suggest that AM 580 inhibits tumor proliferation, via reducing the level of RARγ. AM 580 is an activator of RAR β and RAR γ.