Zaurategrast|cas 455264-31-0|DC Chemicals

Zaurategrast|cas 455264-31-0|DC Chemicals

Zaurategrast(CDP-323) is an oral α4-integrin inhibitor.

IC50 value:

Target: α4-integrin

CDP323 significantly decreased the capacity of lymphocytes to bind vascular adhesion molecule-1 (VCAM-1) and the expression of α4-integrin on VCAM-1-binding cells.CDP323 at daily doses of 1000 or 2000 mg induced significant increases in total lymphocyte count and suppressed VCAM-1 binding by reducing unbound very late antigen-4 expression on lymphocytes.

Product Name: Zaurategrast|Cat No: DC9490|Cas: 455264-31-0|Molecule Formular: C26H25BrN4O3|Molecule Weight: 521.4057|Other names: Zaurategrast

Zaurategrast(CDP-323) is an oral α4-integrin inhibitor.
CDP323 significantly decreased the capacity of lymphocytes to bind vascular adhesion molecule-1 (VCAM-1) and the expression of α4-integrin on VCAM-1-binding cells.CDP323 at daily doses of 1000 or 2000 mg induced significant increases in total lymphocyte count and suppressed VCAM-1 binding by reducing unbound very late antigen-4 expression on lymphocytes.

For research only, not for human use!