2016年6月12日星期日

Sobetirome|cas 211110-63-3|DC Chemicals

Sobetirome|cas 211110-63-3|DC Chemicals

Sobetirome(GC-1; QRX-431) is a member of a class of compounds known as selective thyromimetics.

Product Name: Sobetirome|Cat No: DC9539|Cas: 211110-63-3|Molecule Formular: C20H24O4|Molecule Weight: 328.4022|Other names: Sobetirome

Sobetirome(GC-1; QRX-431) is a member of a class of compounds known as selective thyromimetics.
Sobetirome is thyroid hormone beta-receptor agonist.
Sobetirome selectively binds to and activates TRbeta over TRalpha and this receptor selectivity led to the hypothesis that sobetirome would lower cholesterol through activation of liver TRbeta without stimulating cardiac function through TRalpha activation in the heart. The tissue selective thyromimetic properties of sobetirome have been demonstrated in numerous animal models, which led to its clinical development as a novel cholesterol-lowering agent. Treatment of hypercholestemia obesity, and thyroid proliferative disorders.

For research only, not for human use!

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