Sertindole|cas 106516-24-9|DC Chemicals
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available.
Target: Multi-target
In vitro studies showed that sertindole exerts a potent antagonism at serotonin 5-HT2A, 5-HT2C, dopamine D2, and αl adrenergic receptors.
Product Name: Sertindole|Cat No: DC9536|Cas: 106516-24-9|Molecule Formular: C24H26ClFN4O|Molecule Weight: 440.9409|Other names: Sertindole
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available.
In vitro studies showed that sertindole exerts a potent antagonism at serotonin 5-HT2A, 5-HT2C, dopamine D2, and αl adrenergic receptors. Sertindole offers an alternative treatment option for refractory patients given its good EPS profile, favorable metabolic profile, and comparable efficacy to risperidone. Due to cardiovascular safety concerns, sertindole is available as a second-line choice for patients intolerant to other antipsychotic agents. Sertindole should prove to be a very useful addition to the therapeutic options available for the treatment of psychotic disorders. Sertindole improves negative symptoms, and is also effective for the treatment of neuroleptic-resistant schizophrenia. Sertindole is generally well tolerated and is associated with a low rate of extrapyramidal symptoms (EPS). Thus, sertindole is a useful option in the treatment of patients with schizophrenia.
For research only, not for human use!
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