SB 415286|cas 264218-23-7|DC Chemicals

SB 415286|cas 264218-23-7|DC Chemicals

SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM..

Product Name: SB 415286|Cat No: DC9459|Cas: 264218-23-7|Molecule Formular: C16H10ClN3O5|Molecule Weight: 359.7207|Other names: SB 415286

SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM.
As a result of GSK3 inhibition, SB 415286 stimulates glycogen synthesis in the Chang human liver cell line with an EC50 value of 2.9 uM. SB 415286 also protects primary neurons from death induced by the PI3-kinase pathway.

For research only, not for human use!