IKK 16|cas 873225-46-8|DC Chemicals

IKK 16|cas 873225-46-8|DC Chemicals

IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.

IC50 value: 40 nM(IKK-2); 70 nM(Ikk complex); 200 nM(Ikk-1)

Target: IKK2/1

In vitro: IKK-16 inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells.

Product Name: IKK 16|Cat No: DC9485|Cas: 873225-46-8|Molecule Formular: C28H29N5OS|Molecule Weight: 483.6277|Other names: IKK 16

IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
In vitro: IKK-16 inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells. Although IKK-16 shows activity in the IFNγ-induced expression of β2 microglobulin or HLA-DR, its potency in these assays is 4- to 10-fold weaker.

For research only, not for human use!