GANT 58|cas 64048-12-0|DC Chemicals

GANT 58|cas 64048-12-0|DC Chemicals

GANT 58 is a novel and potent Gli antagonist that inhibits GLI1-induced transcription (IC50 = 5 uM).

Product Name: GANT 58|Cat No: DC9453|Cas: 64048-12-0|Molecule Formular: C24H16N4S|Molecule Weight: 392.4756|Other names: GANT 58

GANT 58 is a novel and potent Gli antagonist that inhibits GLI1-induced transcription (IC50 = 5 uM).
GANT 58 inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity in vivo.

For research only, not for human use!