Exherin (trifluoroacetate)|cas 1135237-88-5|DC Chemicals

Exherin (trifluoroacetate)|cas 1135237-88-5|DC Chemicals

Exherin (ADH-1) trifluoroacetate is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities; selectively and competitively binds to and blocks N-cadherin.

IC50 value:

Target: N-cadherin blocker

ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis.

Product Name: Exherin (trifluoroacetate)|Cat No: DC9532|Cas: 1135237-88-5|Molecule Formular: C24H35F3N8O8S2|Molecule Weight: 684.7087|Other names: Exherin (trifluoroacetate)

Exherin (ADH-1) trifluoroacetate is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities; selectively and competitively binds to and blocks N-cadherin.
ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N-cadherin, a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms; may be upregulated in some aggressive tumors and the endothelial cells and pericytes of some tumor blood vessels.

For research only, not for human use!