L-779,450|L-779450|RAF inhibitor|DC Chemicals

L-779,450|L-779450|RAF inhibitor|DC Chemicals

L-779,450 is a potent, ATP-competitive Raf (Raf kinase) inhibitor (IC50 = 10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively.

Product Name: L-779,450 |Catalog Number: DC8362 |CAS 303727-31-3 |Other names:  |Chemical Name: 2-Chloro-5-[2-Phenyl-5-(4-pyridinyl)-1H-imidazol-4-yl]phenol |Molecule Formular: C20H14ClN3O |MW: 347.8

Potent, ATP-competitive Raf kinase inhibitor (IC50 = 10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively. Suppresses DNA synthesis and induces apoptosis in cells that proliferate in response to Raf-1 and A-Raf but not B-Raf. For the detailed information of L-779,450, the solubility of L-779,450 in water, the solubility of L-779,450 in DMSO, the solubility of L-779,450 in PBS buffer, the animal experiment (test) of  L-779,450, the cell expriment (test) of L-779,450, the in vivo, in vitro and clinical trial test of L-779,450, the EC50, IC50,and affinity,of L-779,450, For the detailed information of L-779,450, the solubility of L-779,450 in water, the solubility of L-779,450 in DMSO, the solubility of L-779,450 in PBS buffer, the animal experiment (test) of  L-779,450, the cell expriment (test) of L-779,450, the in vivo, in vitro and clinical trial test of L-779,450, the EC50, IC50,and affinity,of L-779,450, Please contact DC Chemicals.

For research and scientific purpose only, not for human use.