2015年6月1日星期一

TAPI-0 | MMP Inhibitor | CAS 143457-40-3|DC Chemicals

TAPI-0 | MMP Inhibitor | CAS 143457-40-3|DC Chemicals
Inhibits TNF-α processing. Also a general matrix metalloprotease and TACE inhibitor.

Catlog: DC8132| Product name: TAPI-0 (TNF-α processing inhibitor-0)| Cas: 143457-40-3| Other names: TAPI0,TAPI 0| Molecule Formula: C24H32N4O5| MW: 456.53. Purity: >98%

Price: 100mg: 900 USD; 250mg: 1700 USD; 1000mg: 3200 USD

TAPI-0 is an inhibitor of TACE (IC50 = 50-100 nM) as well as other matrix and membrane metalloproteases.For example, it inhibits meprin (Ki value for human meprin α is 2.2 μM).4 Through these actions TAPI-0 blocks the maturation of cytokines, soluble cytokine receptors, and other proteins that require the action of proteases.

For research and scientific purpose only, not for human use.

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