Pyridostatin(RR 82)|cas 1085412-37-8|supplier|DC Chemicals

Pyridostatin(RR 82)|cas 1085412-37-8|supplier|DC Chemicals
Pyridostatin stabilizes G-quadruplexes, targeting the proto-oncogene SRC and telomeric G-quadruplexes, inducing DNA damage and cell-cycle arrest.

Product name: Pyridostatin trifluoroacetate salt |Cat No. DC8091|Other names: Pyridostatin, RR 82|Cas: 1085412-37-8|Molecule Weight: 596.63(free base)|Molecule Formular: C31H32N8O5.xC2HF3O2| Purity: >98%

Pyridostatin(RR 82) binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).

For research and scientific purpose only, not for human use.