PF-429242(PF429242)|S1P inhibitor|DC Chemicals

PF-429242(PF429242)|S1P inhibitor|DC Chemicals
PF-429242 is a potent inhibitor of S1P(cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease)

Product name: PF 429242 |Cat No. DC8059|Other names: PF-429242,PF429242|Cas: 947303-87-9|Molecule Weight: 482.49|Molecule Formular: C25H35N3O2.2HCl| Purity: >98%

PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV.

For research and scientific purpose only, not for human use.