FRAX597(FRAX 597 )|PAK1 inhibitor|DC Chemicals

FRAX597(FRAX 597 )|PAK1 inhibitor|DC Chemicals
FRAX597 is a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas.

Catlog: DC8154| Product name: FRAX 597| Cas: 1286739-19-2| Other names: FRAX 597,FRAX-597,FRAX597| Molecule Formula: C29H28ClN7OS| MW: 558.1. Purity: >98%

Price: 100mg: 900 USD; 250mg: 1800 USD; 1000mg: 3600 USD

FRAX597 inhibits the proliferation of NF2-deficient schwannoma cells in culture and displayed potent anti-tumor activity in vivo, impairing schwannoma development in an orthotopic model of NF2. These studies identify a novel class of orally available ATP-competitive Group I PAK inhibitors with significant potential for the treatment of NF2 and other cancers.

For research and scientific purpose only, not for human use.