2015年6月22日星期一

CB-839|CB839 glutaminase inhibitor|DC Chemicals

CB-839|CB839 glutaminase inhibitor|DC Chemicals
CB-839 is a potent, selective, reversible and orally bioavailable inhibitor of human glutaminase.

Product name: CB-839 |Cat No. DC8042|Other names: CB-839CB839|Cas: 1439399-58-2|Molecule Weight: 571.1|Molecule Formular: C26H24F3N7O3S| Purity: >98%

CB-839 is an investigational drug that works by inhibiting an enzyme involved in cancer metabolism called glutaminase. CB-839 has been shown to halt the growth of or kill cancer cells across a range of tumor types. The compound has demonstrated antitumor activity in several different tumor models in animals. In preclinical toxicology studies, CB-839 was well tolerated in animals at doses above those shown to inhibit tumor growth. CB-839 has also shown strong synergy with immunomodulatory agents and several kinase inhibitors that target growth factor pathways.
For the detailed information of CB-839, the solubility of CB-839 in water, the solubility of CB-839 in DMSO, the solubility of CB-839 in PBS buffer, the animal experiment (test) of  CB-839, the cell expriment (test) of CB-839, the in vivo, in vitro and clinical trial test of CB-839, the EC50, IC50,and affinity,of CB-839, For the detailed information of CB-839, the solubility of CB-839 in water, the solubility of CB-839 in DMSO, the solubility of CB-839 in PBS buffer, the animal experiment (test) of  CB-839, the cell expriment (test) of CB-839, the in vivo, in vitro and clinical trial test of CB-839, the EC50, IC50,and affinity,of CB-839, Please contact DC Chemicals.

For research and scientific purpose only, not for human use.

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