2015年6月22日星期一

AZD-3988(AZD3988)|DGAT-1 inhibitor|DC Chemicals

AZD-3988(AZD3988)|DGAT-1 inhibitor|DC Chemicals
AZD-3988 is a potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM).

Product name: AZD-3988 |Cat No. DC8060|Other names: AZD-3988,AZD3988|Cas: 892489-52-0|Molecule Weight: 456.44|Molecule Formular: C23H22F2N4O4| Purity: >98%

Potent and selective diacylglycerol acyltransferase (DGAT-1) inhibitor (IC50 = 0.6 nM). Exhibits selectivity for DGAT-1 over DGAT-2, Kv11.1 (hERG) and cytochrome P450 enzymes. Suppresses triacylglyceride (TAG) plasma excursion and adipose tissue TAG synthesis in rats. Reduces body weight of diet-induced obese rats. Cell permeable and orally bioavailable.

For research and scientific purpose only, not for human use.

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