DC Chemicals supplies: Z-VAD-FMK,cas: 187389-52-2,Catalog: DC7570,In stock.
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Product name: Z-VAD-FMK, Synonyms: , cas: 187389-52-2, MW: 467.49, Molecule Formula: C22H30FN3O7
Z-VAD-FMK, cas 187389-52-2, Purity>98%. Best price and quality from DC Chemicals. Cell permeable fluoromethyl ketone (FMK)-derivatized peptides act as effective irreversible Caspase inhibitors with no cytotoxic effects and, therefore, are useful tools for studying Caspase activity.
Z-VAD-FMK (10 mM) inhibits apoptosis in THP.1 cells. Z-VAD-FMK (10 μM) inhibits activation of PARP protease activity in control THP.1 cell lysates. Z-VAD-FMK (10 mM) inhibits the processing of CPP32 in intact THP.1 and Jurkat cells. [1] Z-VAD-FMK (50 μM) cotreatment abolishes the apoptotic morphology of camptothecin-treated HL60 cells. Z-VAD-FMK (50 μM) blocks camptothecin-induced DNA fragmentation in HL60 cells. [2] Z-VAD-FMK (50 μM) inhibits cell death following dSMN dsRNA-induced apoptosis in S2 cells. Z-VAD-FMK (50 μM) increases the percentage of transfected cells surviving from 26% to 63% in S2 cells. [3] Z-VAD-FMK (> 100 μM) enhances TNFα-induced neutrophil apoptosis, lower concentrations (1-30 μM) completely blocks TNFα-stimulated apoptosis in human neutrophils. [4] Z-VAD-FMK (10 mM) inhibits apoptosis in anterior stromal keratocytes. Z-VAD-FMK (10 mM) inhibits apoptosis in anterior stromal keratocytes detected with the TUNEL assay. [5]For the detailed information of Z-VAD-FMK, the solubility of Z-VAD-FMK in water, the solubility of Z-VAD-FMK in DMSO, the solubility of Z-VAD-FMK in PBS buffer, the animal experiment (test) of Z-VAD-FMK, the cell expriment (test) of Z-VAD-FMK, the in vivo, in vitro and clinical trial test of Z-VAD-FMK, the EC50, IC50,and Affinity of Z-VAD-FMK, Please contact DC Chemicals.
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