R-268712 supplier|R268712|DC Chemicals
DC Chemicals provides R-268712, other names: R 268712,R268712, cas: 879487-87-3. In stock.
Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643351；
R-268712, other names: R 268712,R268712, cas: 879487-87-3, Molecule formular: C20H18FN5O, Molecule Weight: 363.39, Chemical name: 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol
Potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 = 2.5 nM). Exhibits ~ 5000-fold selectivity over p38 MAPK. Suppresses development of renal fibrosis in a unilateral ureteral obstruction model. Also reduces proteinuria, glomerulosclerosis and improves renal function in an anti-Thy1 glomerulonephritis model. Orally bioavailable.
For the detailed information of R-268712, the solubility of R-268712 in water, the solubility of R-268712 in DMSO, the solubility of R-268712 in PBS buffer, the animal experiment (test) of R-268712, the cell expriment (test) of R-268712, the in vivo, in vitro and clinical trial test of R-268712, the EC50, IC50,and affinity,of R-268712, Please contact DC Chemicals.
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