EPZ015666 supplier|EPZ-015666|DC Chemicals

EPZ015666 supplier|EPZ-015666|DC Chemicals
DC Chemicals provides EPZ015666, other names: EPZ-015666,EPZ 015666, cas: 1616391-65-1. In stock.

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
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EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs.

EPZ015666, other names: EPZ-015666,EPZ 015666, cas: 1616391-65-1, Molecule formular: C20H25N5O3, Molecule Weight: 383.44, Chemical name: (S)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide

EPZ015666 shows potent cellular activity that blocks symmetric dimethylation of SmD3 and inhibit proliferation of MCL cell lines (Z-138, Granta-519, Maver-1, Mino, and Jeko-1) with IC50 of 96-904 nM.EPZ015666 (200 mg/kg, p.o.) displays robust anti-tumor activity in MCL xenograft animal models.
For the detailed information of EPZ015666, the solubility of EPZ015666 in water, the solubility of EPZ015666 in DMSO, the solubility of EPZ015666 in PBS buffer, the animal experiment (test) of  EPZ015666, the cell expriment (test) of EPZ015666, the in vivo, in vitro and clinical trial test of EPZ015666, the EC50, IC50,and affinity,of EPZ015666, Please contact DC Chemicals.