(S)-Equol|cas 531-95-3|DC Chemicals

(S)-Equol|cas 531-95-3|DC Chemicals

(S)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM).

Product Name: (S)-Equol |Catalog Number: DC8451 |CAS 531-95-3 |Other names:  |Chemical Name:  |Molecule Formular: C15H14O3 |MW: 242.27

Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora.The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein.(S)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM).(S)-equol is also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies. For the detailed information of (S)-Equol, the solubility of (S)-Equol in water, the solubility of (S)-Equol in DMSO, the solubility of (S)-Equol in PBS buffer, the animal experiment (test) of  (S)-Equol, the cell expriment (test) of (S)-Equol, the in vivo, in vitro and clinical trial test of (S)-Equol, the EC50, IC50,and affinity,of (S)-Equol, For the detailed information of (S)-Equol, the solubility of (S)-Equol in water, the solubility of (S)-Equol in DMSO, the solubility of (S)-Equol in PBS buffer, the animal experiment (test) of  (S)-Equol, the cell expriment (test) of (S)-Equol, the in vivo, in vitro and clinical trial test of (S)-Equol, the EC50, IC50,and affinity,of (S)-Equol, Please contact DC Chemicals.

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