(R)-Equol|cas 221054-79-1| DC Chemiclas

(R)-Equol|cas 221054-79-1| DC Chemiclas

In contrast to the estrogen receptor (ER) selectivity of (S)-equol , (R)-equol is a weaker ER agonist that binds to ERα and ERβ with Ki values of 27.4 and 15.4 nM, respectively.

Product Name: (R)-Equol |Catalog Number: DC8450 |CAS 221054-79-1 |Other names: Isoequol |Chemical Name: 3,4-dihydro-3R-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol |Molecule Formular: C15H14O3 |MW: 242.3

Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora.It is a chiral molecule that exists in two enantiomeric forms.In contrast to the estrogen receptor (ER) selectivity of (S)-equol , (R)-equol is a weaker ER agonist that binds to ERα and ERβ with Ki values of 27.4 and 15.4 nM, respectively.The (R)-enantiomer demonstrates higher ER agonist activity at ERα compared to ERβ (EC50 = 66 and 330 nM, respectively). For the detailed information of (R)-Equol, the solubility of (R)-Equol in water, the solubility of (R)-Equol in DMSO, the solubility of (R)-Equol in PBS buffer, the animal experiment (test) of  (R)-Equol, the cell expriment (test) of (R)-Equol, the in vivo, in vitro and clinical trial test of (R)-Equol, the EC50, IC50,and affinity,of (R)-Equol, For the detailed information of (R)-Equol, the solubility of (R)-Equol in water, the solubility of (R)-Equol in DMSO, the solubility of (R)-Equol in PBS buffer, the animal experiment (test) of  (R)-Equol, the cell expriment (test) of (R)-Equol, the in vivo, in vitro and clinical trial test of (R)-Equol, the EC50, IC50,and affinity,of (R)-Equol, Please contact DC Chemicals.

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