NVP-TNKS656|TNKS2 inhibitor|DC Chemicals

NVP-TNKS656|TNKS2 inhibitor|DC Chemicals

NVP-TNKS656(TNKS-656) is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.

Product Name: NVP-TNKS656 |Catalog Number: DC8463 |CAS 1419949-20-4 |Other names: TNKS656; TNKS-656,TNKS 656 |Chemical Name:  |Molecule Formular: C27H34N4O5 |MW: 494.58

NVP-TNKS656(TNKS-656) is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.
NVP-TNKS656 was identified as an orally active antagonist of Wnt pathway activity in the MMTV-Wnt1 mouse xenograft model. With an enthalpy-driven thermodynamic signature of binding, highly favorable physicochemical properties, and high lipophilic efficiency.

For research and scientific purpose only, not for human use.