Nutlin-3b|(+)Nutlin-3|MDM2 inhibitor|DC Chemicals

Nutlin-3b|(+)Nutlin-3|MDM2 inhibitor|DC Chemicals

Nutlin-3b is 150-fold less potent as an inhibitor of p53-MDM2 interaction than (−)-nutlin-3, demonstrating an IC50 value of 13.6 µM.

Product Name: Nutlin-3b |Catalog Number: DC8455 |CAS 675576-97-3 |Other names: Nutlin-3b,nutlin 3b,nutlin3b,(+)Nutlin-3 |Chemical Name:  |Molecule Formular: C30H30Cl2N4O4 |MW: 581.49

(+)-Nutlin-3 is arbitrarily referred to as enantiomer b because it appears as the second peak from chiral purification of racemic nutlin-3 and its absolute stereocenter assignment is not known. It is 150-fold less potent as an inhibitor of p53-MDM2 interaction than (−)-nutlin-3, demonstrating an IC50 value of 13.6 µM. This inactive enantiomer can serve as a useful control for non-MDM2 related cellular activities. For the detailed information of Nutlin-3b, the solubility of Nutlin-3b in water, the solubility of Nutlin-3b in DMSO, the solubility of Nutlin-3b in PBS buffer, the animal experiment (test) of  Nutlin-3b, the cell expriment (test) of Nutlin-3b, the in vivo, in vitro and clinical trial test of Nutlin-3b, the EC50, IC50,and affinity,of Nutlin-3b, For the detailed information of Nutlin-3b, the solubility of Nutlin-3b in water, the solubility of Nutlin-3b in DMSO, the solubility of Nutlin-3b in PBS buffer, the animal experiment (test) of  Nutlin-3b, the cell expriment (test) of Nutlin-3b, the in vivo, in vitro and clinical trial test of Nutlin-3b, the EC50, IC50,and affinity,of Nutlin-3b, Please contact DC Chemicals.

For research and scientific purpose only, not for human use.