AZD3759|AZD-3759|EGFR inhibitor|DC Chemicals

AZD3759|AZD-3759|EGFR inhibitor|DC Chemicals

AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR), with potential antineoplastic activity.

Product Name: AZD-3759 |Catalog Number: DC8472 |CAS 1626387-80-1 |Other names: AZD-3759,AZD 3759,,AZD3759 |Chemical Name: (R)-4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate |Molecule Formular: C22H23ClFN5O3 |MW: 459.14

AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon oral administration, AZD3759 binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. This prevents EGFR-mediated signaling, and may lead to both induction of cell death and inhibition of tumor growth in EGFR-overexpressing cells. EGFR, a receptor tyrosine kinase mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization.

For research and scientific purpose only, not for human use.