PF-04457845|cas 1020315-31-4|DC Chemicals

PF-04457845|cas 1020315-31-4|DC Chemicals

PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.

IC50 value: 7.2 nM

Target: FAAH

It has been well tolerated in human trials even at high dose ranges with no evidence for cognitive dysfunction, and has completed Phase II clinical trials for the treatment of osteoarthritis.

Product Name: PF-04457845|Cat No: DC9442|Cas: 1020315-31-4|Molecule Formular: C23H20F3N5O2|Molecule Weight: 455.4324|Other names: PF-04457845

PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.
It has been well tolerated in human trials even at high dose ranges with no evidence for cognitive dysfunction, and has completed Phase II clinical trials for the treatment of osteoarthritis. From Wikipedia.

For research only, not for human use!